Welcome to My Personal Website!! Your browser does not support the video tag. Hello, I am Pradeep Singh Thakur Ph.D. , M.S.(Pharm.) A passionate researcher, developer, & lifelong learner. Explore my projects & research journey. Let’s connect, collaborate, and create meaningful impact together. Thank you for visiting my website! Pradeep 🚀 15+ Projects Completed ⏳ 9+ Years Research Experience 🧪 Nanotechnologist Advancing Healthcare & Clean Energy through Nanotechnology 💊 Pharmaceutical Scientist Advancing Precision Medicine & Innovative Biosensing 🤖 Computational Geek Exploring AI, Machine Learning, Graphics & Web Wizardry Recent Publications ❮ Development of 3D Porphyrinic Covalent Organic Frameworks for Enhanced Sono-Photodynamic Therapy against Prostate Cancer Inorg. Chem., 2025, 64, 18770-18786. P. S. Thakur, S. Das Pramanik, P. Roy & M. Sankar Copy Citation Read More Fe-Porphyrin-Derived Carbon Nanofiber-Based Nanozymes: Enhanced Peroxidase-Like Activity for Ultrasensitive Glucose and Ascorbic Acid Sensing Mater. Adv., 2025, 2356–2364. P. S. Thakur & M. Sankar Copy Citation Read More Porphyrin-Based Covalent Organic Framework Encapsulating Multiwalled Carbon Nanotubes: A High-Performance Electrocatalyst for Oxygen Reduction Reaction Langmuir, 2025, 10456–10468. P. S. Thakur, V. Singh, V. Ganesan & M. Sankar Copy Citation Read More Green Synthesis of Porphyrin-Based Self-Assembled Nanocubes for Augmented Sono-Photodynamic Inactivation of Bacteria: A Sustainable Approach Towards Advanced Antimicrobial Strategies Nanoscale Adv., 2024, 6123-6128. P. S. Thakur & M. Sankar Copy Citation Read More ❯ Affiliations
Development of 3D Porphyrinic Covalent Organic Frameworks for Enhanced Sono-Photodynamic Therapy against Prostate Cancer Inorg. Chem., 2025, 64, 18770-18786. P. S. Thakur, S. Das Pramanik, P. Roy & M. Sankar Copy Citation Read More
Fe-Porphyrin-Derived Carbon Nanofiber-Based Nanozymes: Enhanced Peroxidase-Like Activity for Ultrasensitive Glucose and Ascorbic Acid Sensing Mater. Adv., 2025, 2356–2364. P. S. Thakur & M. Sankar Copy Citation Read More
Porphyrin-Based Covalent Organic Framework Encapsulating Multiwalled Carbon Nanotubes: A High-Performance Electrocatalyst for Oxygen Reduction Reaction Langmuir, 2025, 10456–10468. P. S. Thakur, V. Singh, V. Ganesan & M. Sankar Copy Citation Read More
Green Synthesis of Porphyrin-Based Self-Assembled Nanocubes for Augmented Sono-Photodynamic Inactivation of Bacteria: A Sustainable Approach Towards Advanced Antimicrobial Strategies Nanoscale Adv., 2024, 6123-6128. P. S. Thakur & M. Sankar Copy Citation Read More
About I am a self-driven, quick starter, and passionate researcher with a curious mind, thriving on solving complex and challenging real-world problems. My professional journey revolves around the fascinating realms of nanotechnology, pharmaceutical science, chemical engineering, analytical chemistry, organic chemistry, and biotechnology. Currently, I am deeply immersed in the developement of porphyrin-based nanomaterials for advancing Medicinal and material Technologies. My focus revolves around crafting self-assembled nanoparticles, covalent organic frameworks, and metal-organic frameworks. The overarching goal of my work is to harness these materials for their potential applications in antimicrobial & anticancer sono-photodynamic therapy and sono-photocatalysis. In essence, I am actively involved in creating nanomaterials with unique porphyrin structures that demonstrate efficacy in combating bacteria & cancer through light & ultrasound-based processes, while also exhibiting remarkable sono-photocatalytic properties. This research holds significant promise for advancing materials that can find applications in the realms of medicine, particularly in the domain of antibacterial & anticancer treatments, and environmental science, with potential implications in sono-photocatalytic processes. Driven by relentless curiosity, I find joy in exploring the intersections of various scientific disciplines, continuously pushing the boundaries of what is possible. My work is fueled by a passion for making meaningful contributions to the advancement of healthcare and the development of sustainable green energy resources for the betterment of human lives. Additionally, I am leveraging Artificial Intelligence and machine learning tools to drive advancements in the same domains, enhancing the impact and efficacy of my research. As you navigate through my website, I invite you to delve into the projects, research endeavors, and experiences that have shaped my professional journey. Thank you for visiting, and I look forward to connecting with fellow enthusiasts, collaborators, and those who share a similar zeal for innovation and scientific exploration. Scientific Expertise ❮ ❯ Managerial & Soft skills Leadership Led teams in organizing and managing various successful events. Time Management Knowledge and experience in project & event management responsibilities. Communication Working experience with international & national teams and collaborators. Willingness to Learn I'm always eager to learn new things and skills to improve my overall performance. Tech Expertise C++ Python HTML JavaScript CSS MATLAB SQL VS code GIT AWS KNIME Jupyter Lab Pipeline Pilot PyTorch TensorFlow Daniel lewis 14 June, 2021 Pradeep was hired to create a corporate identity. We were very pleased with the work done. She has a lot of experience and is very concerned about the needs of client. Lorem ipsum dolor sit amet, ullamcous cididt consectetur adipiscing elit, seds do et eiusmod tempor incididunt ut laborels dolore magnarels alia. Affiliations
Resume Education Indian Institute of Technology (IIT) Roorkee Roorkee, India Doctor of Philosophy (Ph.D.) in Nanotechnology July 2018 – April 2025 Thesis Title – "Porphyrin-based Nanomaterials for Advanced Applications" Nanomedicine & Nanotheranostics, Supramolecular Reticular Chemistry, Green Chemistry, Nano-biosensors, Tissue Engineering, Sustainable & Green Energy Resources. National Institute of Pharmaceutical Education and Research (NIPER) S.A.S. Nagar Mohali, India M.S. (Pharm.) in Medicinal Chemistry Aug 2016 – June 2018 Thesis Title – "Studies on the Carbohydrates extracted from Costus Speciosus Rhizomes" Supramolecular Medicinal Chemistry, Carbohydrate & Peptide Chemistry, Glyco-Nanotechnology, Natural Product Chemistry, Phytomedicines, Computational Chemistry, CAD, DBMS. Dr. Hari Singh Gour Vishwavidyalaya (A Central University) Sagar, India Bachelor of Pharmacy (B. Pharm.), Pharmaceutical Sciences Jul 2012 – June 2016 Project Title – "Development of Nanoemulsion as Topical Drug Delivery System" Pharmaceutical Nanotechnology, Biopharmaceutics (QbD and DoE), Bio- & Pharmacoinformatics, Pharmacognosy, Pharmacology, Industrial Pharmacy, Quality Control & Assurance, Novel Drug Delivery Systems. Research Experience Senior Research Fellow July 2018 — Present Centre for Nanotechnology & Department of Chemistry, IIT Roorkee Roorkee, India Conducted advanced research on the design, synthesis, and application of functional nanostructures for light- and ultrasound-triggered antimicrobial/anticancer therapies, biosensing, and photocatalysis, with a strong focus on eco-friendly healthcare and sustainable energy solutions. This work encompassed pioneering green synthesis methods, integrating nanomaterials with biological systems, employing advanced analytical techniques, and leveraging machine learning for material optimization. 🏆 Key Research Achievements: 🧬 Stimuli-Responsive Nanostructures – Designed dual-responsive (sono/photo) nano-self-assemblies and 3D-COFs for bacterial inactivation, cancer therapy, and sustainable photocatalysis. 🌱 Green Synthesis Innovations – Developed the first-ever eco-friendly synthesis route for porphyrin-based self-assembled nanocubes and other low-toxicity nanomaterials (carbon dots, graphene quantum dots, MXene hybrids). 🧪 Advanced Material–Biointerface Facilities – Established lab-scale capabilities for COF/MOF/metallocage synthesis and mammalian & bacterial cell/tissue culture to enable integrated bio-nanomaterial studies. 🔬 Biosensing Platforms – Fabricated nanozyme-active electrospun carbon nanofibers and hybrid aptamer–nanozyme biosensors in lab-on-a-chip systems for real-time glucose, cancer biomarker, and pathogen detection. 🤖 AI-Driven Material Optimization – Applied machine learning–assisted SAR models to enhance porphyrin nanophotosensitizers for photodynamic (PDT) and sonodynamic (SDT) therapies. ⚡ Sustainable Energy & Catalysis – Engineered COF/MOF–CNT hybrids for oxygen reduction and electro-/photocatalytic clean energy applications. 👨🏫 Leadership & Collaboration – Mentored junior researchers, ensured lab safety compliance, and contributed to grant proposals, project planning, and scientific publications. Industrial Research Trainee May 2017 — Jul 2017 Technology Development Centre - Dosage form (Formulation) : GMP Manufacturing Pilot Plant Facility, NIPER Mohali, India Completed hands-on pharmaceutical industrial training in a GMP-aligned manufacturing environment, gaining practical exposure to formulation development, manufacturing processes, quality systems, regulatory affairs, and global compliance through real-world case studies. 🏆 Key Training Modules: ⚗ Formulation & Process Development – Dosage form design, SOP drafting, and preparation of Validation Master Plan (VMP) and Site Master File (SMF). 🏭 GMP & Regulatory Compliance – Implementation of cGMP, FDA inspection readiness, and global Drug Regulatory Affairs procedures. 🔬 Analytical & Validation Techniques –Hands-on use of HPLC, GC, LC-MS; pharmaceutical validation and equipment qualification as per regulatory guidelines. 🧪 Cleanroom & Contamination Control – HVAC design principles, cleanroom classification, and prevention of cross-contamination. 🚚 Tech Transfer & Supply Chain Security – Scale-up processes, technology transfer, serialization (track & trace, e-pedigree), and import/export compliance (DGFT and global standards). Master's Research Fellow Aug 2016 — Jun 2018 Department of Medicinal Chemistry, NIPER Mohali Mohali, India Investigated bioactive carbohydrate- and peptide-based therapeutics within phytomedicine, focusing on enhancing bioavailability, efficacy, and targeted delivery for managing diabetes and antimicrobial resistance. Research integrated natural product chemistry, glyconanotechnology, computational chemistry, and advanced analytical characterization techniques. 🏆 Key Research Achievements: 🌿 Anti-Diabetic Phytochemicals – Studied carbohydrates extracted from Costus speciosus rhizomes, conducting structure elucidation, biological screening, and characterization via HPLC, UV-Vis, and Mass Spectrometry. ⚗ Glyconanoparticle Development – Synthesized carbohydrate-based nanostructures to improve the pharmacokinetic profile of plant-derived anti-diabetic compounds. 🧬 Glycopeptide Engineering – Designed and synthesized glycopeptide derivatives using solid-phase peptide synthesis (SPPS) for targeted antimicrobial applications. 💻 Computational Chemistry – Applied molecular docking and structure–activity relationship (SAR) modeling to evaluate interaction profiles of plant-derived compounds with target enzymes. Undergraduate Researcher Aug 2015 — April 2016 Department of Pharmaceutical Sciences (DOPS), Dr. Hari Singh Gour Central University Sagar, India Investigated diverse methods for formulating nanoemulsions and evaluated their multifunctional applications across pharmaceuticals, cosmetics, and food industries. Focused on optimizing formulation parameters to achieve stability, efficiency, and enhanced performance for targeted applications. 🏆 Key Research Achievements: ⚗ Formulation & Optimization – Developed high- and low-energy nanoemulsion preparation methods, optimizing droplet size, surfactant concentration, and processing conditions for stability and efficacy. 💊 Pharmaceutical & Cosmetic Applications – Created drug-loaded and cosmetic nanoemulsions to enhance solubility, targeted delivery, skin penetration, and active ingredient stability. 🍽 Food Industry Solutions – Designed functional food nanoemulsions for improved nutrient stability, controlled release, and product shelf-life. Leadership Experience Evaluator – State Level Camp (Level-II) Examination, Vidyarthi Vigyan Manthan 2023–24, organized by NCSM (Ministry of Culture) & NCERT (Ministry of Education), Govt. of India – Dec 17, 2023. Student Coordinator – Indian Academy of Sciences Meeting & Lecture Workshop – Nov 16–18, 2023. Student Organizer – G20 Impact Summit, IIT Roorkee – Aug 2–3, 2023. Contingent Leader – Inter-Bhawan Cultural General Championship (GC) 1.0 – Mar–Apr 2023. Social & Cultural Secretary – Vigyan Bhawan, IIT Roorkee – 2022–24. Core Member – ThinK India Club (TIC), IIT Roorkee. Student Coordinator – Workshop on Solar Photovoltaics (WSPV-22), IIT Roorkee – Jul 18–24, 2022. Student Coordinator – SPARK Poster Session, IIT Roorkee – 2019. Mentor & Active Member – Child Rights and You (CRY), IIT Roorkee Chapter – 2019–Present. Head, Organizing Committee – Chemophile (Weekly Seminar Club), NIPER-Mohali – 2017–18. Core Member – Chenab Boys Hostel Committee, NIPER, Mohali – 2017–18. Memberships Registered Pharmacist at the Pharmacy Council of India (PCI). Life Member of the Chemical Research Society of India (CRSI). Member of The Indian Institute of Metals (IIM). Honors & Awards Winner of Intra-Bhawan Quiz competition held at Indian Institute of Technology, Roorkee, 2019. Doctoral fellowship from Ministry of Education (MoE), Government of India (GOI), New Delhi, India, 2018. Selected as Junior Research Fellow (JRF) at Council of Scientific and Industrial Research–Indian Institute of Integrative Medicine (CSIR–IIIM), Jammu, 2018. Winner of "Mindcraft event" organized by Department of Pharmaceutical Management, NIPER SAS Nagar, 2017. 1st runner-up prize in Carrom Tournament in Spandan (Intra-Niper Annual Sports and Cultural Event) at NIPER, Mohali, 2017. Semi-Finalist in Chess Tournament in Spandan (Intra-Niper Annual Sports and Cultural Event) at NIPER, Mohali, 2017. Master's fellowship from Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, New Delhi, India, 2016. Qualified NIPER JEE (Joint Entrance Examination), 2016. Selected for Admission to M.Pharm. programme in the Department of Pharmaceutical Engineering & Technology, Indian Institute of Technology (IIT) BHU, for the Session 2016-17. Qualified Dr. Hari Singh Gour Central University-Postgraduate Entrance Examination, 2016. Qualified Graduate Pharmacy Aptitude Test (GPAT), 2016 and eligble for Post Graduate Scholarship provided by the All India Council for Technical Education (AICTE), Government of India. State level quiz competition WINNER (2010, 2011, and 2012). Vidya Bharati Akhil Bhartiya Shiksha Sansthan, New Delhi, India. Certifications & Trainings 🔬Scientific & Health Research Scientific Writing & Publishing – École Polytechnique Psychological First Aid – Johns Hopkins University 💻Technology & Data Science: Google Professional Certificates Data Analytics (8-course) Advanced Data Analytics (7-course) Project Management (6-course) Digital Marketing & E-commerce (7-course) Cybersecurity (8-course) IT Automation with Python Machine Learning for Business Professionals Business Intelligence IT Support UX Design Managing Machine Learning Projects with Google Cloud 📜Intellectual Property & Policy WHO–WIPO–WTO Executive Course on Access to Medical Technologies General Course on Intellectual Property – WIPO Patent Filing & Commercialization 💰Fundraising & Grant Seeking Trainings Fundraising Essentials: What is Nonprofit Fundraising? Fundraising Essentials: Soliciting and Stewarding Donors How to Secure Funding – ECR Edition Grant Seeking Essentials: Complete 5-Series Course My skills Research & Development 90% Intellectual property rights (IPR) 85% UX & Graphic Design 80% Web developement 70%
Research All Advanced Healthcare Systems AI-Driven Nanomaterial Design Sustainable Energy Resources Select category All Advanced Healthcare Systems AI-Driven Nanomaterial Design Sustainable Energy Resources Advanced Healthcare Systems Development of innovative nanomaterials for advanced healthcare applications by combining nanotechnology, medicinal chemistry, and biomedical engineering to create targeted, multifunctional platforms for therapeutics, diagnostics, and precision medicine. 🧪 Design of porphyrin-based nanostructures: self-assembled NPs, electrospun nanofibers, COFs, MOFs, & hybrid nanomaterials 💊 Targeted drug delivery for cancer and infectious diseases 🔬 Anticancer and antimicrobial photo- & sonodynamic therapies 📈 Sensitive biosensing for diagnostics and precision medicine 🚀 Engineering multifunctional platforms for precise & minimally invasive highly effective therapeutic solutions Advancing next-generation nanomaterials to address critical challenges in healthcare and enable personalized and precision medicine. AI-driven Rational Design of Photosensitizers AI-driven rational design of photosensitizers using advanced machine learning (ML)-based structure–activity relationship (SAR) models, integrating computational predictions and data-driven optimization, to accelerate the discovery and development of highly efficient and targeted nanomaterials for healthcare. 🤖 Rational design with AI/ML modeling for faster discovery of PSs. 🔬 Optimizing singlet oxygen yield, photostability, and selectivity. 💡 Developing nanomaterials for cancer, antimicrobial treatment, and imaging. ⏱️ Reducing experimental time and cost via AI/ML predictions. 🚀 Creating next-generation PSs with improved performance. Advancing data-driven nanotechnology for precision medicine, healthcare innovation, and next-gen therapeutic solutions. Sustainable & Renewable Energy Resources Focus on developing nanomaterials for sustainable and renewable energy, emphasizing clean energy generation and environmental remediation. Expertise in porphyrin-based nanostructures, COFs, MOFs, and hybrid nanomaterials for designing advanced photocatalysts and electrocatalysts. ⚡ Efficient catalysis for OER, HER, ORR, and CO₂RR ☀️ Solar energy conversion with tailored porphyrinic frameworks 🔋 H₂ generation & fuel cells through advanced catalyst design 🌍 CO₂ reduction and utilization for carbon management ♻️ Eco-friendly, cost-effective technologies for clean energy goals Advancing nanotechnologies to support green energy transitions, carbon neutrality, and climate change mitigation.